Overview

  • Product name
    XTP (aqueous solution)
  • Description
    Adenylyl and guanylyl cyclase inhibitor
  • Biological description
    Adenylyl and guanylyl cyclase inhibitor. GTP analog. Competitively inhibits transducin-catalyzed GTP hydrolysis.
  • Purity
    > 95%

Properties

  • Molecular weight
    524.16
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C10H15N4O15P3
  • CAS Number
    6253-56-1
  • Storage instructions
    Store at -20°C (desiccating conditions).
  • Solubility overview

    Supplied in water (100 mM)

  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:
  • Yanachkov I  et al. Synthesis and effect of nonhydrolyzable xanthosine triphosphate derivatives on prenylation of Rab5D136N. Mol Pharmacol 51:47-51 (1997). Read more (PubMed: 9016345) »
  • Klinker JF & Seifert R Functionally nonequivalent interactions of guanosine 5'-triphosphate, inosine 5'-triphosphate, and xanthosine 5'-triphosphate with the retinal G-protein, transducin, and with Gi-proteins in HL-60 leukemia cell membranes. Biochem Pharmacol 54:551-62 (1997). Read more (PubMed: 9337071) »
  • Kang C  et al. Replacement of Asp333 with Asn by site-directed mutagenesis changes the substrate specificity of Escherichia coli adenylosuccinate synthetase from guanosine 5'-triphosphate to xanthosine 5'-triphosphate. J Biol Chem 269:24046-9 (1994). Read more (PubMed: 7929056) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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