Overview

  • Product nameAnti-XTP4 antibody
    See all XTP4 primary antibodies
  • Description
    Rabbit polyclonal to XTP4
  • SpecificityThese antibodies have been fully characterized for cross-reactivity with other members of the amplicon related proteins. Expected to cross-react with Mouse (100% identity with RIKEN cDNA 1810046J19), Rat (100% identity with similar to RIKEN cDNA 1810046J19) and Zebrafish (88% identity with "selenoprotein W2a).
  • Tested applicationsSuitable for: ELISA, WB, IP, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Zebrafish
  • Immunogen

    Synthetic peptide:

    CEIEINGQLVFSKLENGGF

    , corresponding to Internal sequence amino acids 66-83 of Human XTP4.

  • General notesBriefly centrifuge antibodies to collect liquid at the bottom.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab14762 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/15000 - 1/20000.
WB Use at an assay dependent concentration. Predicted molecular weight: 13.8 kDa.
IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

Target

  • FunctionIncreases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.
  • Tissue specificityAmong normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level).
  • Sequence similaritiesBelongs to the SelWTH family.
  • Post-translational
    modifications
    Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation.
  • Cellular localizationCytoplasm > cytosol. Cell membrane. Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.
  • Information by UniProt
  • Database links
  • Alternative names
    • C17orf37 antibody
    • C17orf37 homolog antibody
    • C35 antibody
    • chromosome 17 open reading frame 37 antibody
    • HBV X transactivated gene 4 protein antibody
    • HBV X-transactivated gene 4 protein antibody
    • HBV XAg transactivated protein 4 antibody
    • HBV XAg-transactivated protein 4 antibody
    • MGC14832 antibody
    • Mien1 antibody
    • MIEN1_HUMAN antibody
    • Migration and invasion enhancer 1 antibody
    • ORB3 antibody
    • Protein C17orf37 antibody
    • Protein C35 antibody
    • RDX12 antibody
    • Redox protein, 12-KD antibody
    • XTP4 antibody
    see all

References for Anti-XTP4 antibody (ab14762)

ab14762 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"