Overview

  • Product nameAnti-XTP4 antibody [EPR2678]
    See all XTP4 primary antibodies
  • Description
    Rabbit monoclonal [EPR2678] to XTP4
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human XTP4.

  • Positive control
    • SKBR3 cell lysate.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • PurityTissue culture supernatant
  • ClonalityMonoclonal
  • Clone numberEPR2678
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab92499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/1000 - 1/10000. Detects a band of approximately 12 kDa (predicted molecular weight: 12 kDa).

    Is unsuitable for Flow Cyt, ICC, IHC-P or IP.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionIncreases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.
    • Tissue specificityAmong normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level).
    • Sequence similaritiesBelongs to the SelWTH family.
    • Post-translational
      modifications
      Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation.
    • Cellular localizationCytoplasm > cytosol. Cell membrane. Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.
    • Information by UniProt
    • Database links
    • Alternative names
      • C17orf37 antibody
      • C17orf37 homolog antibody
      • C35 antibody
      • chromosome 17 open reading frame 37 antibody
      • HBV X transactivated gene 4 protein antibody
      • HBV X-transactivated gene 4 protein antibody
      • HBV XAg transactivated protein 4 antibody
      • HBV XAg-transactivated protein 4 antibody
      • MGC14832 antibody
      • Mien1 antibody
      • MIEN1_HUMAN antibody
      • Migration and invasion enhancer 1 antibody
      • ORB3 antibody
      • Protein C17orf37 antibody
      • Protein C35 antibody
      • RDX12 antibody
      • Redox protein, 12-KD antibody
      • XTP4 antibody
      see all

    Anti-XTP4 antibody [EPR2678] images

    • Anti-XTP4 antibody [EPR2678] (ab92499) at 1/1000 dilution + SKBR3 cell lysate at 10 µg

      Secondary
      goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 12 kDa
      Observed band size : 12 kDa

    References for Anti-XTP4 antibody [EPR2678] (ab92499)

    This product has been referenced in:
    • Nakao LS  et al. Mechanism-based proteomic screening identifies targets of thioredoxin-like proteins. J Biol Chem 290:5685-95 (2015). Read more (PubMed: 25561728) »

    See 1 Publication for this product

    Product Wall

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"