Overview

  • Product name
  • Description
    Rabbit polyclonal to XYLT2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Dog
  • Immunogen

    Recombinant fragment, corresponding to a region within internal sequence amino acids 272-520 of Human XYLT2 (Uniprot ID: Q9H1B5).

  • Positive control
    • 293T, A431, HeLa, Raji whole cell lysate; HeLa cells
  • General notes
    Store as a concentrated solution.

Properties

Applications

Our Abpromise guarantee covers the use of ab155193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 97 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    Probably catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes (By similarity). Its enzyme activity has not been demonstrated.
  • Tissue specificity
    Widely expressed. Expressed at higher level in kidney and pancreas.
  • Pathway
    Glycan metabolism; chondroitin sulfate biosynthesis.
    Glycan metabolism; heparan sulfate biosynthesis.
  • Sequence similarities
    Belongs to the glycosyltransferase 14 family. XylT subfamily.
  • Post-translational
    modifications
    Contains disulfide bonds.
  • Cellular localization
    Endoplasmic reticulum membrane. Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Peptide O xylosyltransferase 1 antibody
    • Peptide O-xylosyltransferase 1 antibody
    • protein xylosyltransferase 2 antibody
    • PXYLT2 antibody
    • UDP-D-XYLOSE:PROTEOGLYCAN CORE PROTEIN BETA-D-XYLOSYLTRANSFERASE 2 antibody
    • UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase antibody
    • XT II antibody
    • XT-II antibody
    • XT2 antibody
    • Xylosyltransferase 2 antibody
    • Xylosyltransferase II antibody
    • xylT II antibody
    • XylT-II antibody
    • XYLT2 antibody
    • XYLT2_HUMAN antibody
    see all

Images

  • Anti-XYLT2 antibody (ab155193) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size: 97 kDa



    7.5% SDS PAGE
  • Immunofluorescent analysis of methanol-fixed HeLa cells labeling XYLT2 with ab155193 at 1/500 dilution (green). Alpha tubulin filaments were labeled red.

References

ab155193 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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