Anti-Yersinia pestis F1 antigen antibody [1.F.1] (ab31428)

Overview

  • Product nameAnti-Yersinia pestis F1 antigen antibody [1.F.1]
    See all Yersinia pestis F1 antigen primary antibodies
  • Description
    Mouse monoclonal [1.F.1] to Yersinia pestis F1 antigen
  • SpecificityRecognizes capsule bearing strains of Y. pestis.
  • Tested applicationsSuitable for: IHC-Fr, IHC-Pmore details
  • Species reactivity
    Reacts with Yersinia pestis Not yet tested in other species.
  • Immunogen

    Purified F1 antigen of Y. pestis vaccine strain EB.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: 40% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number1.F.1
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab31428 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

Target

  • RelevanceYersinia pestis is a gram-negative coccobacillus belonging to the Enterobacteriaceae. Yersinia pestis is primarily a rodent pathogen, with humans being an accidental host when bitten by an infected rat flea.  The flea draws viable Y. pestis organisms into its intestinal tract. Some Y. pestis in the flea are then regurgitated when the flea gets its blood meal thus transferring the infection to a new host. While growing in the flea, Y. pestis loses its capsular layer, which is made of the F1 (or fraction 1) capsule antigen. Most of the organisms are phagocytosed and killed by the polymorphonuclear leukocytes in the human host. A few bacilli are taken up by tissue macrophages. The macrophages are unable to kill Y. pestis and provide a protected environment for the organisms to synthesize their virulence factors.
  • Cellular localizationSecreted
  • Alternative names
    • Caf1 antibody
    • F1 capsule antigen antibody

References for Anti-Yersinia pestis F1 antigen antibody [1.F.1] (ab31428)

ab31428 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"