Overview

  • Product nameAnti-Yes1 antibody
    See all Yes1 primary antibodies
  • Description
    Mouse monoclonal to Yes1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein with tag, corresponding to amino acids 1-544 of Human Yes1

  • Positive control
    • A431 whole cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab61206 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 61 kDa (predicted molecular weight: 61 kDa).
ELISA Use at an assay dependent dilution.

Target

  • FunctionPromotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Autophosphorylated.
  • Cellular localizationCytoplasm > cytosol. In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.
  • Information by UniProt
  • Database links
  • FormThis protein is known to be similar in amino acid sequence to HCK (P08631), LCK (P06239), FYN (P06241), SRC (P12931), and LYN (P07948). Therefore, cross-reactivity with these homologous proteins may be observed. We would be happy to provide immunogen alignment information upon request.
  • Alternative names
    • c Yes antibody
    • Cellular Yes 1 protein antibody
    • Cellular Yes1 protein antibody
    • HsT441 antibody
    • P61 YES antibody
    • p61-Yes antibody
    • Proto oncogene tyrosine protein kinase YES antibody
    • Proto-oncogene c-Yes antibody
    • Tyrosine-protein kinase Yes antibody
    • v yes 1 Yamaguchi sarcoma viral oncogene homolog 1 antibody
    • Viral oncogene yes 1 homolog 1 antibody
    • Viral oncogene yes1 homolog 1 antibody
    • Yamaguchi sarcoma oncogene antibody
    • Yes 1 antibody
    • Yes antibody
    • YES proto oncogene 1, Src family tyrosine kinase antibody
    • YES_HUMAN antibody
    • YES1 antibody
    • YES1 proto oncogene, Src family tyrosine kinase antibody
    see all

Anti-Yes1 antibody images

  • Anti-Yes1 antibody (ab61206) at 1 µg/ml + A431 whole cell lysate at 50 µg/ml

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 61 kDa
    Observed band size : 61 kDa

References for Anti-Yes1 antibody (ab61206)

ab61206 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"