Anti-Yes1 antibody [EPR3173] (ab109265)


  • Product nameAnti-Yes1 antibody [EPR3173]
    See all Yes1 primary antibodies
  • Description
    Rabbit monoclonal [EPR3173] to Yes1
  • Tested applicationsSuitable for: WB, IP, IHC-P, ICCmore details
    Unsuitable for: Flow Cyt
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human Yes1.

  • Positive control
    • WB: U-87MG, SW480 and Jurkat cell lysates IHC-P: Human colon tissue
  • General notes

    Produced using Abcam's RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5, 675, 063 and/or 7, 429, 487.

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab109265 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 60 kDa (predicted molecular weight: 61 kDa).
IP 1/10 - 1/100.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC 1/50 - 1/100.
  • Application notesIs unsuitable for Flow Cyt.
  • Target

    • FunctionPromotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.
    • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
      Contains 1 protein kinase domain.
      Contains 1 SH2 domain.
      Contains 1 SH3 domain.
    • Post-translational
    • Cellular localizationCytoplasm > cytosol. In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.
    • Information by UniProt
    • Database links
    • FormThis protein is known to be similar in amino acid sequence to HCK (P08631), LCK (P06239), FYN (P06241), SRC (P12931), and LYN (P07948). Therefore, cross-reactivity with these homologous proteins may be observed. We would be happy to provide immunogen alignment information upon request.
    • Alternative names
      • c Yes antibody
      • Cellular Yes 1 protein antibody
      • Cellular Yes1 protein antibody
      • HsT441 antibody
      • P61 YES antibody
      • p61-Yes antibody
      • Proto oncogene tyrosine protein kinase YES antibody
      • Proto-oncogene c-Yes antibody
      • Tyrosine-protein kinase Yes antibody
      • v yes 1 Yamaguchi sarcoma viral oncogene homolog 1 antibody
      • Viral oncogene yes 1 homolog 1 antibody
      • Viral oncogene yes1 homolog 1 antibody
      • Yamaguchi sarcoma oncogene antibody
      • Yes 1 antibody
      • Yes antibody
      • YES proto oncogene 1, Src family tyrosine kinase antibody
      • YES_HUMAN antibody
      • YES1 antibody
      • YES1 proto oncogene, Src family tyrosine kinase antibody
      see all

    Anti-Yes1 antibody [EPR3173] images

    • ab109265 at 1/50 dilution staining Yes1 in Human colon by Immunohistochemistry, Paraffin-embedded tissue.
    • All lanes : Anti-Yes1 antibody [EPR3173] (ab109265) at 1/1000 dilution

      Lane 1 : U-87 MG cell lysate
      Lane 2 : SW480 cell lysate
      Lane 3 : Jurkat cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size : 61 kDa
      Observed band size : 60 kDa (why is the actual band size different from the predicted?)

    References for Anti-Yes1 antibody [EPR3173] (ab109265)

    ab109265 has not yet been referenced specifically in any publications.

    Product Wall

    I have included the antigen retrieval protocol below:

    Antigen Retrieval Solution: 0.01M Sodium Citrate Buffer, pH 6.0

    Antigen Retrieval

    Immerse slides into staining dish containing Antigen Retrieval Solution.


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