• Product name
    Anti-z DNA antibody
  • Description
    Sheep polyclonal to z DNA
  • Tested applications
    Suitable for: IP, In situ hybridizationmore details
  • Immunogen



  • Form
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: PBS, pH 7.5
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab2079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent dilution.
In situ hybridization Use at an assay dependent dilution. See below; Cerna, A. et al, European journal of Histochemistry.


  • Relevance
    Z-DNA is one of the many possible double helical structures of DNA. It is a left-handed double helical structure in which the double helix winds to the left in a zig-zag pattern (instead of to the right, like the more common B-DNA form). Z-DNA is thought to be one of three biologically active double helical structures along with A- and B-DNA.


This product has been referenced in:
  • Safina A  et al. FACT is a sensor of DNA torsional stress in eukaryotic cells. Nucleic Acids Res 45:1925-1945 (2017). Read more (PubMed: 28082391) »
  • Lu P  et al. The Za domain of fish PKZ converts DNA hairpin with d(GC)n inserts to Z-conformation. Acta Biochim Biophys Sin (Shanghai) 45:1062-8 (2013). Read more (PubMed: 24113090) »

See all 3 Publications for this product

Customer reviews and Q&As

Having checked with the lab, we can confirm that a preparation of Z-DNA (i.e. left-handed DNA) of sufficient purity has been injected.
I am sorry that we are unable to provide more details, but I hope this information is nevertheless helpful to yo...

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Thank you for contacting us and your patience.
Unfortunately, the antigen used to produce this product was made a few years ago in a laboratory at a private university. Most information regarding this antibody is propriety, however, I can tell you...

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Thank you for your inquiry. The lab where this antibody is produced informed me that, unfortunately, at this time they do not have a specific DNA sequence that could be used as a positive control for immunoprecipitation. We will updat...

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Thank you for contacting us. Z-DNA antibody was raised in sheep using brominated poly-(DG-DC)-left handed DNA (Z-DNA) complexed to methylated BSA as the immunogen. I asked the lab about a recommended positive control. I will contact you...

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Thank you for your enquiry. Your question is indeed an interesting one. The two most commonly used techniques for the preparation of chromatin are sonication and a mild micrococcal nuclease digestion. They can both be employed for use in cross link...

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Thank you for your enquiry. There is a reference on the datasheet for this antibody(ab2079) which as far as I can tell recommends a dilution of 1:10 for ISH. European Journal of Histochemistry. 2004 48 (1) 49-56. Z-DNA a new in situ marker for tran...

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