Anti-ZADH1 antibody - N-terminal (ab171135)

Overview

  • Product name
    Anti-ZADH1 antibody - N-terminal
    See all ZADH1 primary antibodies
  • Description
    Rabbit polyclonal to ZADH1 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human ZADH1 aa 72-102 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q8N8N7

  • Positive control
    • 293 cell line lysates, Human liver tissue

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab171135 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab171135 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 38 kDa.

Target

  • Function
    Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
  • Tissue specificity
    Widely expressed.
  • Sequence similarities
    Belongs to the NADP-dependent oxidoreductase L4BD family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 15 oxoprostaglandin 13 reductase antibody
    • 15 oxoprostaglandin delta 13 reductase antibody
    • 15-oxoprostaglandin 13-reductase antibody
    • DKFZp686P10120 antibody
    • FLJ39091 antibody
    • FLJ99229 antibody
    • PGR 2 antibody
    • PGR2 antibody
    • PRG-2 antibody
    • Prostaglandin reductase 2 antibody
    • PTGR 2 antibody
    • PTGR2 antibody
    • PTGR2_HUMAN antibody
    • Zinc binding alcohol dehydrogenase domain containing 1 antibody
    • Zinc binding alcohol dehydrogenase domain containing protein 1 antibody
    • Zinc-binding alcohol dehydrogenase domain-containing protein 1 antibody
    see all

Images

  • Anti-ZADH1 antibody - N-terminal (ab171135) at 1/100 dilution + 293 cell line lysates at 35 µg

    Predicted band size: 38 kDa

  • Immunohistochemistry analysis of formalin fixed and paraffin embedded Human liver tissue, labelling ZADH1 with ab171135 at 1/10 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

References

ab171135 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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