Overview

  • Product nameAnti-ZBTB7A antibody
    See all ZBTB7A primary antibodies
  • Description
    Rabbit polyclonal to ZBTB7A
  • SpecificityAt least two isoforms of ZBTB7A are known to exist; ab106592 will recognize both isoforms. Predicted to not cross-react with other ZBTB protein family members.
  • Tested applicationsSuitable for: ICC/IF, WB, ICC, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A 16 amino acid synthetic peptide from near the N-terminus of Human ZBTB7A (AAH84568).

  • Positive control
    • Human ovary tissue lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG

Associated products

Applications

Our Abpromise guarantee covers the use of ab106592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 61 kDa.
ICC Use a concentration of 2.5 µg/ml.
IHC-P Use at an assay dependent concentration.

Target

  • FunctionPlays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
  • Tissue specificityWidely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).
  • Sequence similaritiesContains 1 BTB (POZ) domain.
    Contains 4 C2H2-type zinc fingers.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp547O146 antibody
    • Factor binding IST protein 1 antibody
    • Factor that binds to inducer of short transcripts protein 1 antibody
    • FBI-1 antibody
    • FBI1 antibody
    • HIV-1 1st-binding protein 1 antibody
    • HIV-1 inducer of short transcripts binding protein antibody
    • HIV-1 inducer of short transcripts-binding factor 1 antibody
    • Leukemia/lymphoma-related factor antibody
    • LRF antibody
    • lymphoma related factor antibody
    • MGC99631 antibody
    • POK erythroid myeloid ontogenic factor antibody
    • Pokemon antibody
    • POZ and Krueppel erythroid myeloid ontogenic factor antibody
    • TIP21 antibody
    • TTF-I-interacting peptide 21 antibody
    • ZBT7A_HUMAN antibody
    • ZBTB7 antibody
    • ZBTB7A antibody
    • Zinc finger and BTB domain containing 7A antibody
    • zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein antibody
    • Zinc finger and BTB domain-containing protein 7A antibody
    • Zinc finger protein 857A antibody
    • Zinc finger- and BTB domain-containing protein 7 antibody
    • ZNF857A antibody
    see all

Anti-ZBTB7A antibody images

  • Immunofluorescence of ZBTB7A in Human ovary tissue with ab106592 at 20 ug/mL.
  • Lane 1 : Anti-ZBTB7A antibody (ab106592) at 1 µg/ml
    Lane 2 : Anti-ZBTB7A antibody (ab106592) at 2 µg/ml

    Lane 1 : Human ovary tissue lysate
    Lane 2 : Human ovary tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 61 kDa
  • Immunohistochemistry of ZBTB7A in Human ovary tissue with ab106592 at 2.5 µg/ml.

References for Anti-ZBTB7A antibody (ab106592)

ab106592 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"