The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesIP: 2 to 5 ug/mg of lysate.
WB: 1/2500 - 1/10000. Predicted molecular weight: 111 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionExhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY, possibly preventing its dephosphorylation. May act as a transcriptional repressor. Down-regulates CA9 expression.
Tissue specificityHighly expressed in smooth muscle, pancreas and testis.