The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes IP: Use at 2-5µg/mg of lysate.
WB: Use at a concentration of 0.2 µg/ml. Predicted molecular weight: 120 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionExhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY, possibly preventing its dephosphorylation. May act as a transcriptional repressor. Down-regulates CA9 expression.
Tissue specificityHighly expressed in smooth muscle, pancreas and testis.