Overview

  • Product nameAnti-ZDHHC17 antibody
    See all ZDHHC17 primary antibodies
  • Description
    Rabbit polyclonal to ZDHHC17
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 397-446 (VALFYNFGKS WKSDPGIIKA TEEQKKKTIV ELAETGSLDL SIFCSTCLIR) of Human ZDHHC17 (NP_056151).

  • Positive control
    • HeLa cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab80886 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100.
WB Use a concentration of 1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 70 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceZDHHC17 is a neuronal palmitoyl transferase. Palmitoylation is critical for trafficking and function of signaling molecules, neurotransmitter receptors, and synaptic scaffolding proteins in neurons. ZDHHC17 causes cellular transformation. It has been shown that mRNA encoding ZDHHC17 is up-regulated in a number of types of human tumors, thus ZDHHC17 and other PATs (palmitoyl acyltransferases) are potential targets for new anticancer drugs.
  • Cellular localizationGolgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
  • Database links
  • Alternative names
    • DHHC 17 antibody
    • DHHC domain containing 17 antibody
    • HIP14 antibody
    • HIP3 antibody
    • HSPC294 antibody
    • huntingtin interacting protein 14 antibody
    • huntingtin interacting protein 3 antibody
    • Huntingtin interacting protein H antibody
    • HYPH antibody
    • KIAA0946 antibody
    • Putative MAPK activating protein PM11 antibody
    • Putative NF kappa B activating protein 205 antibody
    • ZDHHC 17 antibody
    • zinc finger antibody
    • Zinc finger DHHC domain containing 17 antibody
    • Zinc finger DHHC domain containing protein 17 antibody
    • Zinc finger DHHC type containing 17 antibody
    see all

Anti-ZDHHC17 antibody images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human pineal tissue labelling ZDHHC17 with ab80886 at 1/100. A Cy3-conjugated donkey anti-rabbit IgG (1/200) was used as the secondary antibody. Positive staining shown in the cytoplasm of vesicles and processes of pinealocytes. Magnification: 20X. Exposure time: 0.5 - 2.0 seconds. Left - DAPI. Middle - ZDHHC17. Right - Merge.
  • Anti-ZDHHC17 antibody (ab80886) at 1 µg/ml (in 5% skim milk / PBS buffer) + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 70 kDa
    Observed band size : 70 kDa
    Gel concentration 12%

References for Anti-ZDHHC17 antibody (ab80886)

ab80886 has not yet been referenced specifically in any publications.

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