The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-ZDHHC17 antibody (ab31298)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
DHHC domain containing 17
huntingtin interacting protein 14
huntingtin interacting protein 3
Huntingtin interacting protein H
Putative MAPK activating protein PM11
Putative NF kappa B activating protein 205
Zinc finger DHHC domain containing 17
Zinc finger DHHC domain containing protein 17
Zinc finger DHHC type containing 17
RelevanceZDHHC17 is a neuronal palmitoyl transferase. Palmitoylation is critical for trafficking and function of signaling molecules, neurotransmitter receptors, and synaptic scaffolding proteins in neurons.
ZDHHC17 causes cellular transformation. It has been shown that mRNA encoding ZDHHC17 is up-regulated in a number of types of human tumors, thus ZDHHC17 and other PATs (palmitoyl acyltransferases) are potential targets for new anticancer drugs.