Overview

  • Product name
    Anti-ZFP100 / ZNF473 antibody
    See all ZFP100 / ZNF473 primary antibodies
  • Description
    Rabbit polyclonal to ZFP100 / ZNF473
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide corresponding to a region within N terminal amino acids 185-215 of Human ZFP100/ ZNF473 (UniProt ID: Q8WTR7).

  • Positive control
    • NCI-H460 cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab103023 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab103023 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 100 kDa.

Target

  • Function
    Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.
  • Sequence similarities
    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 20 C2H2-type zinc fingers.
    Contains 1 KRAB domain.
  • Domain
    The C2H2-type zinc finger 2 to 6 are necessary and sufficient for discrete Cajal bodies localization. The C2H2-type zinc finger 5 to 10 are necessary and sufficient for interaction with LSM11. The C2H2-type zinc finger 2 to 8 are necessary for interaction with the SLBP/RNA complex in the histone pre-mRNAs. The C2H2-type zinc finger 2 to 10 confer activity in histone pre-mRNA processing.
  • Cellular localization
    Nucleus. Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA.
  • Information by UniProt
  • Database links
  • Alternative names
    • HZFP100 antibody
    • Zfp 100 antibody
    • Zfp-100 antibody
    • Zinc finger protein 100 homolog antibody
    • Zinc finger protein 473 antibody
    • zinc finger protein ZFP100 antibody
    • ZN473_HUMAN antibody
    • Znf473 antibody
    see all

Images

  • Anti-ZFP100 / ZNF473 antibody (ab103023) at 1/100 dilution + NCI-H460 cell lysate at 35 µg

    Predicted band size : 100 kDa

References

ab103023 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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