Overview

  • Product name
    Anti-ZFYVE16 antibody
  • Description
    Rabbit polyclonal to ZFYVE16
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 380-410 of Human ZFYVE16 (isoform 2), conjugated to KLH.

  • Positive control
    • K562 cell line lysates; Human lung tissue

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab103683 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab103683 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: for isoform 2, 88 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.
  • Tissue specificity
    Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes.
  • Sequence similarities
    Contains 1 FYVE-type zinc finger.
  • Domain
    The FYVE-type zinc finger is necessary and sufficient for its localization into early endosomes and mediates the association with PI3P.
  • Cellular localization
    Cytoplasm. Early endosome membrane. Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI035632 antibody
    • B130024H06Rik antibody
    • B130031L15 antibody
    • DKFZp686E13162 antibody
    • Endofin antibody
    • Endosomal associated FYVE domain protein antibody
    • Endosome associated FYVE domain protein antibody
    • Endosome-associated FYVE domain protein antibody
    • KIAA0305 antibody
    • KIAA0305; antibody
    • mKIAA0305 antibody
    • OTTMUSP00000029589 antibody
    • RGD1564784 antibody
    • ZFY16_HUMAN antibody
    • ZFYVE16 antibody
    • Zinc finger FYVE domain containing protein 16 antibody
    • Zinc finger FYVE domain-containing protein 16 antibody
    • Zinc finger, FYVE domain containing 16 antibody
    see all

Anti-ZFYVE16 antibody images

  • Anti-ZFYVE16 antibody (ab103683) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size : for isoform 2, 88 kDa
  • ab103683, at a 1/50 dilution, staining ZFYVE16 in formalin fixed, paraffin embedded Human lung tissue by Immunohistochemistry, followed by peroxidase-conjugated secondary antibody and DAB staining.

References for Anti-ZFYVE16 antibody (ab103683)

ab103683 has not yet been referenced specifically in any publications.

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