Overview

  • Product name
    Anti-ZFYVE28 antibody
  • Description
    Rabbit polyclonal to ZFYVE28
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    KLH conjugated synthetic peptide corresponding to a region within C terminal amino acids 611-642 of Human ZFYVE28 (NP_001166130.1, NP_001166131.1, NP_066023.2, NP_001166127.1, NP_001166129.1).

  • Positive control
    • Mouse heart tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab107913 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 96 kDa.

Target

  • Function
    Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated.
  • Sequence similarities
    Belongs to the lst-2 family.
    Contains 1 FYVE-type zinc finger.
  • Domain
    The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not monoubiquitinated at Lys-87.
  • Post-translational
    modifications
    Monoubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes.
  • Cellular localization
    Cytoplasm > cytosol. Early endosome membrane. Localizes to early endosome membrane in absence of Lys-87 monoubiquitination. Localizes to cytosol when monoubiquitinated.
  • Information by UniProt
  • Database links
  • Alternative names
    • hLst2 antibody
    • Lateral signaling target protein 2 homolog antibody
    • LST2 antibody
    • LST2_HUMAN antibody
    • LYST2 antibody
    • MGC43699 antibody
    • MGC61592 antibody
    • zfyve28 antibody
    • Zinc finger FYVE domain containing 28 antibody
    • Zinc finger FYVE domain-containing protein 28 antibody
    see all

Images

  • Anti-ZFYVE28 antibody (ab107913) at 1/100 dilution + Mouse heart tissue lysate at 35 µg

    Predicted band size : 96 kDa

References

ab107913 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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