Anti-Zinc finger MIZ domain-containing protein 1 antibody (ab113294)

Overview

  • Product name
    Anti-Zinc finger MIZ domain-containing protein 1 antibody
    See all Zinc finger MIZ domain-containing protein 1 primary antibodies
  • Description
    Rabbit polyclonal to Zinc finger MIZ domain-containing protein 1
  • Specificity
    ab113294 antibody will recognize all three known Zinc finger MIZ domain-containing protein 1 isoforms. It is predicted to not cross-react with other PIAS protein family members or other Human proteins based on sequence homology.
  • Tested applications
    Suitable for: ICC/IF, WB, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to 15 amino acids near the N terminal of Human Zinc finger MIZ domain-containing protein 1

  • Positive control
    • A562 cell lysate tested by WB.

Properties

Applications

Our Abpromise guarantee covers the use of ab113294 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 115 kDa.
ICC Use a concentration of 10 µg/ml.

Target

  • Function
    Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation.
  • Tissue specificity
    Expressed most abundantly in ovary and, at lower levels, in prostate, spleen and testis. Weak expression, if any, in thymus, small intestine, colon and peripheral blood leukocytes.
  • Sequence similarities
    Contains 1 SP-RING-type zinc finger.
  • Domain
    The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity. This activity is inhibited by the N-terminus in the full-length protein.
  • Cellular localization
    Nucleus speckle. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • hZIMP10 antibody
    • KIAA1224 antibody
    • MIZ antibody
    • PIAS like protein hZimp10 antibody
    • PIAS like protein on chromosome 10 antibody
    • PIAS like protein Zimp10 antibody
    • PIAS-like protein Zimp10 antibody
    • RAI 17 antibody
    • Retinoic acid induced 17 antibody
    • Retinoic acid induced protein 17 antibody
    • Retinoic acid-induced protein 17 antibody
    • TRAFIP10 antibody
    • Zimp10 antibody
    • Zinc finger containing Miz1 PIAS like protein on chromosome 10 antibody
    • Zinc finger MIZ domain-containing protein 1 antibody
    • Zinc finger MIZ-type containing 1 antibody
    • Zmiz1 antibody
    • ZMIZ1_HUMAN antibody
    see all

Images

  • Immunofluorescence of Zinc finger MIZ domain-containing protein 1 in K562 cells with ab113294 at 20 ug/mL.
  • All lanes : Anti-Zinc finger MIZ domain-containing protein 1 antibody (ab113294) at 0.5 µg/ml

    Lane 1 : K562 cell lysate without blocking peptide
    Lane 2 : K562 cell lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 115 kDa
  • Immunocytochemical analysis of K562 cells, staining Zinc finger MIZ domain-containing protein 1 with ab113294 at 10 µg/ml.

References

ab113294 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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