• Product nameAnti-ZIP Kinase antibody [EPR1636Y]
    See all ZIP Kinase primary antibodies
  • Description
    Rabbit monoclonal [EPR1636Y] to ZIP Kinase
  • Specificityab51602 recognizes ZIP Kinase.
  • Tested applicationsSuitable for: WB, Flow Cytmore details
    Unsuitable for: ICC/IF or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human ZIP Kinase aa 400 to the C-terminus (C terminal).
    Database link: O43293

  • Positive control
    • HeLa cell lysate.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.


Associated products


Our Abpromise guarantee covers the use of ab51602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 53 kDa (predicted molecular weight: 53 kDa).
Flow Cyt 1/10.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

  • Application notesIs unsuitable for ICC/IF or IP.
  • Target

    • FunctionSerine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection.
    • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
      Contains 1 protein kinase domain.
    • Post-translational
      Ubiquitinated. Ubiquitination mediated by the UBE2D3 E3 ligase does not lead to proteasomal degradation, but influences promyelocytic leukemia protein nuclear bodies (PML-NBs) formation in the nucleus.
      Autophosphorylated. Phosphorylated by ROCK1.
    • Cellular localizationNucleus. Cytoplasm. Nucleus > PML body. Relocates to the cytoplasm on binding PAWR where the complex appears to interact with actin filaments (By similarity). Localizes to promyelocytic leukemia protein nuclear bodies (PML-NBs). Associates to centromeres from prophase to anaphase.
    • Information by UniProt
    • Database links
    • Alternative names
      • DAP kinase 3 antibody
      • DAP like kinase antibody
      • DAP-like kinase antibody
      • Dapk 3 antibody
      • DAPK3 antibody
      • DAPK3_HUMAN antibody
      • Death associated kinase 3 antibody
      • Death associated protein kinase 3 antibody
      • Death-associated protein kinase 3 antibody
      • Dlk antibody
      • EC antibody
      • FLJ36473 antibody
      • MYPT1 kinase antibody
      • ZIP antibody
      • ZIP kinase antibody
      • ZIP kinase isoform antibody
      • ZIP-kinase antibody
      • ZIPK antibody
      • zipper-interacting protein kinase antibody
      see all

    Anti-ZIP Kinase antibody [EPR1636Y] images

    • Anti-ZIP Kinase antibody [EPR1636Y] (ab51602) at 1/1000 dilution + HeLa cell lysate at 10 µg

      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 53 kDa
      Observed band size : 53 kDa

    References for Anti-ZIP Kinase antibody [EPR1636Y] (ab51602)

    This product has been referenced in:
    • Marina O  et al. Serologic markers of effective tumor immunity against chronic lymphocytic leukemia include nonmutated B-cell antigens. Cancer Res 70:1344-55 (2010). WB ; Human . Read more (PubMed: 20124481) »

    See 1 Publication for this product

    Product Wall

    Application Western blot
    Sample Mouse Cell lysate - whole cell (Heart)
    Gel Running Conditions Reduced Denaturing (12% acrylamide)
    Loading amount 25 µg
    Specification Heart
    Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C

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    Submitted May 11 2015