Overview

  • Product name
  • Description
    Rabbit polyclonal to ZMYM2
  • Specificity
    At least three isoforms of ZMYM2 are known to exist; ab106624 will detect only the longest isoform. It is predicted to not cross react with other ZMYM protein family members.
  • Tested applications
    Suitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 17 amino acid peptide near the amino terminus of Human ZMYM2 (CAH71822).

  • Positive control
    • EL4 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab106624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 0.125 - 0.25 µg/ml. Predicted molecular weight: 155 kDa.

Target

  • Function
    May function as a transcription factor.
  • Involvement in disease
    Note=A chromosomal aberration involving ZMYM2 may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Translocation t(8;13)(p11;q12) with FGFR1. SCLL usually presents as lymphoblastic lymphoma in association with a myeloproliferative disorder, often accompanied by pronounced peripheral eosinophilia and/or prominent eosinophilic infiltrates in the affected bone marrow.
  • Sequence similarities
    Contains 9 MYM-type zinc fingers.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Form
    There are 2 isoforms produced by alternative splicing.
  • Alternative names
    • FIM antibody
    • Fused in myeloproliferative disorders protein antibody
    • MYM antibody
    • RAMP antibody
    • Rearranged in an atypical myeloproliferative disorder antibody
    • Rearranged in atypical myeloproliferative disorder protein antibody
    • SCLL antibody
    • ZFP 198 antibody
    • Zinc finger MYM type containing 2 antibody
    • Zinc finger MYM type protein 2 antibody
    • Zinc finger MYM-type protein 2 antibody
    • Zinc finger protein 198 antibody
    • Zinc finger protein198 antibody
    • zinc finger, MYM-type 2 antibody
    • ZMYM 2 antibody
    • ZMYM2 antibody
    • ZMYM2_HUMAN antibody
    • ZNF 198 antibody
    • ZNF198 antibody
    see all

Images

  • Immunofluorescence of ZMYM2 in HeLa cells with ab106624 at 20 ug/mL.
  • Lane 1 : Anti-ZMYM2 antibody (ab106624) at 0.125 µg/ml
    Lane 2 : Anti-ZMYM2 antibody (ab106624) at 0.25 µg/ml

    Lane 1 : EL4 cell lysate
    Lane 2 : EL4 cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 155 kDa
  • Immunocytochemistry of ZMYM2 in HeLa cells with ab106624 at 10 ug/mL.

References

ab106624 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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