Overview

  • Product nameAnti-ZMYM2 antibody
    See all ZMYM2 primary antibodies
  • Description
    Rabbit polyclonal to ZMYM2
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Guinea pig, Cow, Dog, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • Immunogen

    Synthetic peptide corresponding to a region between residues 1327 and 1377 of Human ZMYM2 (NP_003444.1).

  • Positive control
    • Human Controls: Anaplastic Thyroid Carcinoma, Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Ovarian Carcinoma, Small Cell Lung Cancer, Stomach Adenocarcinoma Mouse Controls: Teratoma

Properties

Applications

Our Abpromise guarantee covers the use of ab114996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections

Target

  • FunctionMay function as a transcription factor.
  • Involvement in diseaseNote=A chromosomal aberration involving ZMYM2 may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Translocation t(8;13)(p11;q12) with FGFR1. SCLL usually presents as lymphoblastic lymphoma in association with a myeloproliferative disorder, often accompanied by pronounced peripheral eosinophilia and/or prominent eosinophilic infiltrates in the affected bone marrow.
  • Sequence similaritiesContains 9 MYM-type zinc fingers.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • FormThere are 2 isoforms produced by alternative splicing.
  • Alternative names
    • FIM antibody
    • Fused in myeloproliferative disorders protein antibody
    • MYM antibody
    • RAMP antibody
    • Rearranged in atypical myeloproliferative disorder protein antibody
    • SCLL antibody
    • ZFP 198 antibody
    • Zinc finger MYM type protein 2 antibody
    • Zinc finger MYM-type protein 2 antibody
    • Zinc finger protein 198 antibody
    • Zinc finger protein198 antibody
    • zinc finger, MYM-type 2 antibody
    • ZMYM 2 antibody
    • ZMYM2 antibody
    • ZMYM2_HUMAN antibody
    • ZNF 198 antibody
    • ZNF198 antibody
    see all

Anti-ZMYM2 antibody images

  • ab114996, at a 1/250 dilution, staining ZMYM2 in formalin fixed paraffin embedded Human small cell lung cancer by Immunohistochemistry. Detected using DAB staining.
  • ab114996, at a 1/250 dilution, staining ZMYM2 in formalin fixed paraffin embedded Human breast carcinoma by Immunohistochemistry. Detected using DAB staining.
  • ab114996, at a 1/250 dilution, staining ZMYM2 in formalin fixed paraffin embedded Mouse teratoma by Immunohistochemistry. Detected using DAB staining.

References for Anti-ZMYM2 antibody (ab114996)

ab114996 has not yet been referenced specifically in any publications.

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