Application notes This antibody gave a positive result in ELISA against the immunizing peptide (ab48177).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionBinds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'.
Sequence similaritiesBelongs to the krueppel C2H2-type zinc-finger protein family. Contains 7 C2H2-type zinc fingers.
Baran-Gale J et al. An integrative transcriptomics approach identifies miR-503 as a candidate master regulator of the estrogen response in MCF-7 breast cancer cells. RNA22:1592-603 (2016).
Read more (PubMed: 27539783) »
Nguyen NT et al. A functional interplay between ZNF217 and estrogen receptor alpha exists in luminal breast cancers. Mol Oncol8:1441-57 (2014).
Read more (PubMed: 24973012) »