Overview

  • Product name
  • Description
    Goat polyclonal to ZNF364
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog
  • Immunogen

    Synthetic peptide:

    C-DQDNRANERGHQTH

    , corresponding to internal sequence amino acids 97-110 of Human ZNF364

  • Positive control
    • HEPG2 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab52016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    Peptide ELISA: Antibody detection limit dilution 1:32,000.
    WB: Use at a concentration of 0.3 - 1.0 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 34 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Acts as an E2-dependent E3 ubiquitin-protein ligase. May be involved in endocytic trafficking.
    • Tissue specificity
      Expressed at extremely low levels in normal breast, prostate, lung, colon. Higher levels of expression are detected in heart, skeletal muscle, testis as well as in breast and prostate cancer cells.
    • Pathway
      Protein modification; protein ubiquitination.
    • Sequence similarities
      Contains 1 RING-type zinc finger.
    • Post-translational
      modifications
      RING-type zinc finger-dependent and E2-dependent autoubiquitination.
    • Cellular localization
      Cytoplasm > cytosol. The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes.
    • Information by UniProt
    • Database links
    • Alternative names
      • BCA2 antibody
      • Breast cancer associated gene 2 antibody
      • CL469780 antibody
      • E3 ubiquitin-protein ligase RNF115 antibody
      • Rabring 7 antibody
      • RING finger protein 115 antibody
      • RN115_HUMAN antibody
      • RNF115 antibody
      • Zinc finger protein 364 antibody
      see all

    Images

    References

    ab52016 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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