Anti-UBR3 antibody (ab169188)
Key features and details
- Mouse polyclonal to UBR3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-UBR3 antibody -
Description
Mouse polyclonal to UBR3 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Recombinant fragment corresponding to Human UBR3 aa 1100-1900.
Database link: Q6ZT12 -
Positive control
- UBR3 transfected 293T cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab169188 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 212 kDa.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 212 kDa. |
Target
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Function
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. -
Pathway
Protein modification; protein ubiquitination. -
Sequence similarities
Belongs to the UBR1 family.
Contains 1 RING-type zinc finger.
Contains 1 UBR-type zinc finger. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 130507 Human
- Entrez Gene: 68795 Mouse
- SwissProt: Q6ZT12 Human
- SwissProt: Q5U430 Mouse
- Unigene: 379548 Human
- Unigene: 314576 Mouse
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Alternative names
- DKFZp434P117 antibody
- DKFZp686N10185 antibody
- E3 ubiquitin-protein ligase UBR3 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (0)
ab169188 has not yet been referenced specifically in any publications.