Overview

  • Product name
    Anti-ZNF653 antibody
  • Description
    Rabbit polyclonal to ZNF653
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: NVNCLKNVVI WYEDHKHRCP YEPHLAELDP TFGLYTTAVW QCEAGHRYFQ DLHSPLKPLS DSDPDSDKVG NGLVAGSSDS SSSGS, corresponding to amino acids 119-203 of Human ZNF653.

  • Positive control
    • Human cerebral cortex tissue; RT 4 and U 251 MG lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab121769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • Function
    Transcriptional repressor. May repress NR5A1, PPARG, NR1H3, NR4A2, ESR1 and NR3C1 transcriptional activity.
  • Tissue specificity
    Highly expressed in testis, cerebellum, temporal lobe, hippocampus and the adrenal gland. Moderately expressed in spleen, uterus, thymus, pancreas, kidney, stomach and rectum.
  • Sequence similarities
    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 5 C2H2-type zinc fingers.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 67 kDa zinc finger protein antibody
    • Zinc finger protein 653 antibody
    • Zinc finger protein Zip67 antibody
    • ZIP67 antibody
    • ZN653_HUMAN antibody
    • Znf653 antibody
    see all

Images

  • ab121769 at 1/50 dilution staining ZNF653 in paraffin embedded Human cerebral cortex tissue by Immunohistochemistry.
  • All lanes : Anti-ZNF653 antibody (ab121769) at 1/250 dilution

    Lane 1 : RT 4 cell lysate
    Lane 2 : U 251 MG cell lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver tissue lysate
    Lane 5 : Human tonsil tissue lysate

    Developed using the ECL technique

References

ab121769 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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