The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 87 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
FunctionTranscription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of genes involved in neuron development, such as KDM5C.
Tissue specificityExpressed in neural tissues.
Involvement in diseaseMental retardation, X-linked, ZNF711-related
Sequence similaritiesBelongs to the krueppel C2H2-type zinc-finger protein family. Contains 12 C2H2-type zinc fingers.