Overview

  • Product nameAnti-ZNF750 antibody
    See all ZNF750 primary antibodies
  • Description
    Rabbit polyclonal to ZNF750
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to amino acids 73-187 of Human ZNF750.

  • Positive control
    • Human stomach tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab121730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Perform Heat Induced Epitope Retrieval (HIER) at pH 6 using a pressure boiler as heat source.

Target

  • Tissue specificityExpressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts.
  • Involvement in diseaseDefects in ZNF750 are the cause of Seborrhea-like dermatitis with psoriasiform (SLDP) [MIM:610227]. SLDP is characterized by a chronic fine diffuse scaly erythematous rash on the face, particularly on the chin, nasolabial folds and eyebrows, around earlobes and over the scalp. The rash exacerbate in the winter, with emotional stress and after strenuous physical activity. Hyperkeratosis of skin over the elbows, knees, palms, soles and metacarpophalangeal joints is evident. There is no arthralgia, arthritis or neurological disorders.
  • Information by UniProt
  • Database links
  • Alternative names
    • Protein ZNF750 antibody
    • ZFP750 antibody
    • Zinc finger protein 750 antibody
    • ZN750_HUMAN antibody
    • ZNF750 antibody
    see all

Anti-ZNF750 antibody images

  • ab121730 at 1/125 dilution staining ZNF750in Paraffin-embedded Human Stomach tissue by Immunohistochemistry. Note: strong cytoplasmic positivity in parietal cells.

References for Anti-ZNF750 antibody (ab121730)

ab121730 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab121730.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"