• Product nameAnti-ZNFN1A4 antibody
    See all ZNFN1A4 primary antibodies
  • Description
    Rabbit polyclonal to ZNFN1A4
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog
  • Immunogen

    Synthetic peptide: SRLLGPDERL LEKDDSVIVE DSLSEPLGYC DGSGPEPHSP GGIRLPNGKL, corresponding to amino acids 110-159 of Human ZNFN1A4

  • Positive control
    • HepG2 cell lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab49285 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1:312500.

WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 61 kDa (predicted molecular weight: 60 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionDNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems.
  • Tissue specificityHighly expressed in skeletal muscle, low levels of expression in heart, thymus, kidney, liver, and spleen. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K562. Highly expressed in THP-1 and Mo7e-IL3 cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.
  • Sequence similaritiesBelongs to the Ikaros C2H2-type zinc-finger protein family.
    Contains 6 C2H2-type zinc fingers.
  • DomainThe N-terminal zinc fingers are involved in sequence-specific DNA binding and heterotypic associations with other family members.
    C-terminal zinc fingers mediate homodimerization.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • EOS antibody
    • Eos protein antibody
    • IKAROS family zinc finger 4 (Eos) antibody
    • IKAROS family zinc finger 4 antibody
    • Ikaros family zinc finger protein 4 antibody
    • IKZF4 antibody
    • IKZF4_HUMAN antibody
    • KIAA1782 antibody
    • Zinc finger protein Eos (IKAROS family zinc finger protein 4) antibody
    • Zinc finger protein Eos antibody
    • Zinc finger protein, subfamily 1A, 4 (Eos) antibody
    • Zinc finger protein, subfamily 1A, member 4 antibody
    • Zinc finger transcription factor Eos antibody
    • ZNFN1A4 antibody
    see all

Anti-ZNFN1A4 antibody images

  • Lane 1 : molecular weight markers
    Lane 2 : Anti-ZNFN1A4 antibody (ab49285) at 1.25 µg/ml

    Lane 1 : molecular weight markers
    Lane 2 : HepG2 cell lysate at 10 µg

    Lane 1 : molecular weight markers
    Lane 2 : HRP conjugated anti-Rabbit IgG at 1/50,000 -1/100,000 dilution

    Predicted band size : 60 kDa
    Observed band size : 61 kDa (why is the actual band size different from the predicted?)

References for Anti-ZNFN1A4 antibody (ab49285)

ab49285 has not yet been referenced specifically in any publications.

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