Overview

  • Product name
  • Description
    Rabbit polyclonal to ZNRF1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Guinea pig, Cow, Cat, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (GGKQSTAARS RGPFPGVSTD DSAVPPPGGA PHFGHYRTGG GAMGLRSRSV) of Human ZNRF1 (NP_115644).

  • Positive control
    • Human fetal spleen lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab94467 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to substrates. May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin-protein ligase activity.
  • Tissue specificity
    Expressed primarily in the nervous system, with expression higher in developing brain relative to adult. Expressed at low levels in testis and thymus.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Contains 1 RING-type zinc finger.
  • Domain
    The RING-type zinc finger domain is required for E3 ligase activity.
  • Cellular localization
    Endosome. Lysosome. Membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Associated with synaptic vesicle membranes in neurons.
  • Information by UniProt
  • Database links
  • Alternative names
    • B830022L21Rik antibody
    • DKFZp434E229 antibody
    • E3 ubiquitin protein ligase ZNRF1 antibody
    • E3 ubiquitin-protein ligase ZNRF1 antibody
    • EC 6.3.2.- antibody
    • FLJ14846 antibody
    • MGC101991 antibody
    • MGC15430 antibody
    • Nerve injury gene 283 antibody
    • Nerve injury induced gene 283 protein antibody
    • Nerve injury-induced gene 283 protein antibody
    • NIN283 antibody
    • Rnf42 antibody
    • Zinc and ring finger 1 antibody
    • zinc and ring finger protein 1 antibody
    • zinc finger and ring finger protein 1 antibody
    • Zinc/RING finger protein 1 antibody
    • ZNRF 1 antibody
    • znrf1 antibody
    • ZNRF1_HUMAN antibody
    • Zrfp1 antibody
    see all

Anti-ZNRF1 antibody images

  • Anti-ZNRF1 antibody (ab94467) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal spleen lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 24 kDa

References for Anti-ZNRF1 antibody (ab94467)

ab94467 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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