Overview

  • Product nameAnti-ZP4 antibody
    See all ZP4 primary antibodies
  • Description
    Rabbit polyclonal to ZP4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MWLLRCVLLC VSLSLAVSGQ HKPEAPDYSS VLHCGPWSFQ FAVNLNQEAT) of Human ZP4N (NP_067009).

  • Positive control
    • HepG2 cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab105560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 59 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionThe mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor.
  • Tissue specificityOocytes.
  • Sequence similaritiesBelongs to the ZP domain family. ZPB subfamily.
    Contains 1 P-type (trefoil) domain.
    Contains 1 ZP domain.
  • DomainThe ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
  • Post-translational
    modifications
    Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
  • Cellular localizationSecreted > extracellular space > extracellular matrix and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Processed zona pellucida sperm-binding protein 4 antibody
    • ZBP antibody
    • Zona pellucida B protein antibody
    • Zona pellucida glycoprotein 4 antibody
    • Zona pellucida protein B antibody
    • Zona pellucida sperm binding protein 4 antibody
    • Zp-4 antibody
    • ZP1 antibody
    • ZP4 antibody
    • ZP4_HUMAN antibody
    • ZPB antibody
    see all

Anti-ZP4 antibody images

  • All lanes : Anti-ZP4 antibody (ab105560) at 0.5 µg/ml

    Lane 1 : Molecular weight marker
    Lane 2 : HepG2 cell lysate at 10 µg


    Predicted band size : 59 kDa

References for Anti-ZP4 antibody (ab105560)

ab105560 has not yet been referenced specifically in any publications.

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