Overview

  • Product name
    Anti-ZP4 antibody
  • Description
    Rabbit polyclonal to ZP4
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 452-482 of Human ZP4 (NP_067009.1).

  • Positive control
    • HepG2 cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab112591 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 59 kDa.

Target

  • Function
    The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor.
  • Tissue specificity
    Oocytes.
  • Sequence similarities
    Belongs to the ZP domain family. ZPB subfamily.
    Contains 1 P-type (trefoil) domain.
    Contains 1 ZP domain.
  • Domain
    The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
  • Post-translational
    modifications
    Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
  • Cellular localization
    Secreted > extracellular space > extracellular matrix and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Processed zona pellucida sperm-binding protein 4 antibody
    • ZBP antibody
    • Zona pellucida B protein antibody
    • Zona pellucida glycoprotein 4 antibody
    • Zona pellucida protein B antibody
    • Zona pellucida sperm binding protein 4 antibody
    • Zp-4 antibody
    • ZP1 antibody
    • ZP4 antibody
    • ZP4_HUMAN antibody
    • ZPB antibody
    see all

Images

  • Anti-ZP4 antibody (ab112591) at 1/100 dilution + HepG2 cell line lysates at 35 µg

    Predicted band size : 59 kDa

References

ab112591 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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