Overview

  • Product name
  • Description
    Goat polyclonal to ZRANB1
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Synthetic peptide:

    KWLDRYRQIRPCTS

    , corresponding to C terminal amino acids 682-695 of Human ZRANB1

  • Positive control
    • Human Cerebellum Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab82132 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 81 kDa.
ELISA Use at an assay dependent dilution.

Target

  • Function
    Positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. May also modulate TNF-alpha signaling.
  • Tissue specificity
    Widely expressed.
  • Sequence similarities
    Belongs to the peptidase C64 family.
    Contains 1 OTU domain.
    Contains 3 RanBP2-type zinc fingers.
  • Domain
    The OTU domain mediates the deubiquitinating activity.
    The RanBP2-type zinc fingers mediate the specific interaction with 'Lys-63'-linked ubiquitin.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp762P2216 antibody
    • hTrabid antibody
    • Trabid antibody
    • TRAF-binding protein domain antibody
    • Ubiquitin thioesterase ZRANB1 antibody
    • Zinc finger Ran-binding domain-containing protein 1 antibody
    • ZRAN1_HUMAN antibody
    • ZRANB1 antibody
    see all

Images

  • Anti-ZRANB1 antibody (ab82132) at 0.1 µg/ml + Human Cerebellum Lysate (35ug in RIPA buffer)

    Predicted band size : 81 kDa

References

ab82132 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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