Overview

  • Product name
  • Description
    Rabbit polyclonal to ZRSR2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Cow, Cat, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 108-157 (KEQWEEQQRK EREEEEQKRQ EKKEKEEALQ KMLDQAENEL ENGTTWQNPE) of Human ZRSR2 (NP_005080).

  • Positive control
    • Human fetal spleen lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab94591 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3'-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.
  • Tissue specificity
    Widely expressed.
  • Sequence similarities
    Contains 2 C3H1-type zinc fingers.
    Contains 1 RRM (RNA recognition motif) domain.
  • Post-translational
    modifications
    Phosphorylated in the RS domain by SRPK1.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCCH type zinc finger antibody
    • CCCH type zinc finger, RNA binding motif and serine/arginine rich protein 2 antibody
    • MGC142014 antibody
    • MGC142040 antibody
    • Renal carcinoma antigen NY REN 20 antibody
    • Renal carcinoma antigen NY-REN-20 antibody
    • RNA-binding motif and serine/arginine rich protein 2 antibody
    • U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related protein 2 antibody
    • U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 antibody
    • U2(RNU2) small nuclear RNA auxiliary factor 1 like 2 antibody
    • U2(RNU2) small nuclear RNA auxiliary factor 1-like 2 antibody
    • U2AF1 RS2 antibody
    • U2AF1L2 antibody
    • U2AF1RS2 antibody
    • U2AF35-related protein antibody
    • U2AFM_HUMAN antibody
    • URP antibody
    • Zinc finger-, CCCH domain-, and RNA-binding motif-containing serine/arginine-rich protein 2 antibody
    • Zrsr2 antibody
    see all

Images

  • Anti-ZRSR2 antibody (ab94591) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal spleen lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 58 kDa

References

ab94591 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you very much for your interest in our antibodies.

I can confirm that both antibodies are not tested and guaranteed for mouse samples.

We usually expect an cross-reaction of an antibody when the immunogne shows 85% or more hom...

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Thank you for your email.

The immunogen of ab50753 also show similarity with mouse >90% so this antibody would also react with mouse samples.

I hope this bit of information will also be helpful.

Thank you for contacting us.

The cross reactivity info we have for these products is entirely based on the sequence homology between human and mouse. The immunogen of ab94951 is about 88% (Blast homology) similar to the mouse sequence so thi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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