Overview

  • Product nameAnti-ZWILCH antibody
    See all ZWILCH primary antibodies
  • Description
    Mouse monoclonal to ZWILCH
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-478 of Human ZWILCH

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab57533 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionEssential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:15824131).
    • Sequence similaritiesBelongs to the ZWILCH family.
    • Cellular localizationChromosome, centromere, kinetochore.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ10036 antibody
      • FLJ16343 antibody
      • homolog of Drosophila Zwilch antibody
      • hZwilch antibody
      • KNTC1AP antibody
      • MGC111034 antibody
      • Protein zwilch homolog antibody
      • ZWILC_HUMAN antibody
      • zwilch antibody
      • zwilch kinetochore protein antibody
      • ZWILCH protein antibody
      • Zwilch, kinetochore associated, homolog antibody
      see all

    Anti-ZWILCH antibody images

    • Western blot against tagged recombinant protein immunogen using ab57533 ZWILCH antibody at 1ug/ml. Predicted band size of immunogen is 79 kDa

    References for Anti-ZWILCH antibody (ab57533)

    ab57533 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57533.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"