The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 88 kDa (predicted molecular weight: 88 kDa).
FunctionProbably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC.
Tissue specificityExpressed in testis, spermatocytes and spermatids (at protein level). Expressed in spermatocytes, spermatids, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.
Sequence similaritiesBelongs to the zyg-11 family. Contains 5 ARM repeats. Contains 3 LRR (leucine-rich) repeats.