Anti-Zyxin (phospho S142) antibody (ab78910)

Overview

  • Product nameAnti-Zyxin (phospho S142) antibody
    See all Zyxin primary antibodies
  • Description
    Rabbit polyclonal to Zyxin (phospho S142)
  • Specificityab78910 detects endogenous levels of Zyxin only when phosphorylated at serine 142.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic phosphopeptide derived from human Zyxin around the phosphorylation site of serine 142 (K-V-SP-S-I)

  • Positive control
    • Extracts from Jurkat cells treated with paclitaxel (1uM, 24hours).

Properties

Applications

Our Abpromise guarantee covers the use of ab78910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 61 kDa.
ELISA 1/10000.

Target

  • RelevanceZyxin binds alpha-actinin and the CRP proteins and is implicated in the regulation and modulation of actin filaments organization, cell adhesion, cell motility, mitosis, and signal transduction. Zyxin may shuttle between focal adhesion plaques and the nucleus. It has been suggested that zyxin is involved in gene transcription by its association with transcription factors in the nucleus.
  • Cellular localizationCytoplasmic, cytoskeletal and Nuclear.
  • Database links
  • Alternative names
    • ESP 2 antibody
    • ESP2 antibody
    • HED 2 antibody
    • HED2 antibody
    • ZYX antibody
    • ZYX protein antibody
    • Zyxin 2 antibody
    • Zyxin2 antibody
    see all

Anti-Zyxin (phospho S142) antibody images

  • All lanes : Anti-Zyxin (phospho S142) antibody (ab78910) at 1/500 dilution

    Lane 1 : Extracts from Jurkat cells, treated with paclitaxel (1uM, 24hours)
    Lane 2 : Extracts from Jurkat cells, treated with paclitaxel (1uM, 24hours) with immunising phosphopeptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 61 kDa
    Observed band size : 61 kDa

References for Anti-Zyxin (phospho S142) antibody (ab78910)

ab78910 has not yet been referenced specifically in any publications.

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