Overview

  • Product name

    (-)-Huperzine A, AChE inhibitor
  • Description

    AChE inhibitor and NMDA receptor antagonist
  • Alternative names

    • Hup A
  • Biological description

    AChE inhibitor and non-competitive NMDA receptor antagonist (Ki = 6 μM, ion channel site). Shows anticonvulsant and antinociceptive effects in vivo. Blood-brain barrier permeable.
  • Purity

    > 97%
  • CAS Number

    102518-79-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Ma T  et al. Huperzine A promotes hippocampal neurogenesis in vitro and in vivo. Brain Res 1506:35-43 (2013). Read more (PubMed: 23454433) »
  • Park P  et al. Intrathecal huperzine A increases thermal escape latency and decreases flinching behavior in the formalin test in rats. Neurosci Lett 470:6-9 (2010). Read more (PubMed: 20026382) »
  • Zhang YH  et al. Spermidine antagonizes the inhibitory effect of huperzine A on [3H]dizocilpine (MK-801) binding in synaptic membrane of rat cerebral cortex. Neurosci Lett 319:107-10 (2002). Read more (PubMed: 11825682) »
  • Gordon RK  et al. The NMDA receptor ion channel: a site for binding of Huperzine A. J Appl Toxicol 21 Suppl 1:S47-51 (2001). Read more (PubMed: 11920920) »

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