Overview

  • Product name

    (+)-JQ1, BET bromodomain inhibitor
  • Description

    Potent, selective and cell-permeable BET bromodomain inhibitor
  • Alternative names

    • (S)-(+)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
    • 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, 1,1-dimethylethyl ester, (6S)-
  • Biological description

    Potent, selective and cell-permeable BET bromodomain inhibitor (Kd values are 50 and 90 nM at BRD4 first and second bromodomains, respectively).

  • Purity

    > 99%
  • CAS Number

    1268524-70-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

See all 2 Publications for this product

Customer reviews and Q&As

Answer


Te confirmo que el producto ab141498 solo se suministra como enantiómero positivo, que es el enantiómero activo que actúa como potente inhibidor de BET. Podría consultar con el laboratorio si fuera posible aislar el isómero negativo, o la mezcla racemica en caso de interesaros.

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