(+)-Valienamine hydrochloride, Carbohydrase inhibitor (ab144812)

Overview

  • Product name

    (+)-Valienamine hydrochloride, Carbohydrase inhibitor
  • Description

    Competitive carbohydrase inhibitor
  • Biological description

    Competitive carbohydrase inhibitor (IC50 values are 0.78 and 1 mM for glucosidase I and II respectively).
  • CAS Number

    38231-86-6

Properties

  • Chemical name

    (1S,2S,3R,6S)-6-Amino-4-(hydroxymethyl)-4-cyclopexene-1,2,3-triol hydrochloride
  • Molecular weight

    211.64
  • Molecular formula

    C7H13NO4.HCl
  • PubChem identifier

    46783223
  • Storage instructions

    Store at -20°C. Store In the Dark. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
  • Solubility overview

    Soluble in Water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=C([C@H]([C@@H]([C@H]([C@H]1N)O)O)O)CO.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Takeuchi M  et al. Inhibitory effect of pseudo-aminosugars on oligosaccharide glucosidases I and II and on lysosomal alpha-glucosidase from rat liver. J Biochem 108:42-6 (1990). Read more (PubMed: 2229010) »
  • Takeuchi M  et al. Inhibitory effect of validamine, valienamine and valiolamine on activities of carbohydrases in rat small intestinal brush border membranes. Chem Pharm Bull (Tokyo) 38:1970-2 (1990). Read more (PubMed: 2268898) »
  • Degwert U  et al. Studies on the biosynthesis of the alpha-glucosidase inhibitor acarbose: valienamine, a m-C7N unit not derived from the shikimate pathway. J Antibiot (Tokyo) 40:855-61 (1987). Read more (PubMed: 3301773) »

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