Anti-1, 3 beta glucan antibody [2G8] (ab233743)
Key features and details
- Mouse monoclonal [2G8] to 1, 3 beta glucan
- Suitable for: ELISA
- Reacts with: Aspergillus nidulans
- Isotype: IgG2b
Overview
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Product name
Anti-1, 3 beta glucan antibody [2G8] -
Description
Mouse monoclonal [2G8] to 1, 3 beta glucan -
Host species
Mouse -
Specificity
ab233743 reacts with 1,3 ß- glucan from Candida albicans, Aspergillus fumigatus and Criptococcus Neoformans and occasionally with ß(1, 6)-linked branching of a single glucosyl residue. ab233743 has been shown to be effective in multiple models of fungal diseases including vaginal and systemic Candida infection, invasive Aspergillosis and Criptococcus Neoformans. -
Tested applications
Suitable for: ELISAmore details -
Species reactivity
Reacts with: Aspergillus nidulans, Candida albicans -
Immunogen
Chemical/ Small Molecule. Laminarin from Laminaria digitata.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Constituents: 2.94% Sodium citrate, 0.61% Tris, 0.05% Glycerol -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
Produced in cell culture media. -
Clonality
Monoclonal -
Clone number
2G8 -
Isotype
IgG2b
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab233743 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (3)
ab233743 has been referenced in 3 publications.
- Narunsky-Haziza L et al. Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions. Cell 185:3789-3806.e17 (2022). PubMed: 36179670
- Keizer EM et al. EphA2-Dependent Internalization of A. fumigatus Conidia in A549 Lung Cells Is Modulated by DHN-Melanin. Front Microbiol 11:534118 (2020). PubMed: 33123097
- Jaumouillé V et al. Coupling of ß2 integrins to actin by a mechanosensitive molecular clutch drives complement receptor-mediated phagocytosis. Nat Cell Biol 21:1357-1369 (2019). PubMed: 31659275