1-(5-Isoquinolinesulfonyl)piperazine hydrochloride, PKC inhibitor (ab143831)

Overview

  • Product name

    1-(5-Isoquinolinesulfonyl)piperazine hydrochloride, PKC inhibitor
  • Description

    Protein kinase C (PKC) and cyclic nucleotide dependent protein kinase inhibitor.
  • Alternative names

    • 1-(5-Isoquinolinylsulfonyl)piperazine MonoHydrochloride
    • HA-100 Hydrochloride
  • Biological description

    Protein kinase C and cyclic nucleotide dependent protein kinase inhibitor.

  • CAS Number

    141543-63-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-(5-Isoquinolinesulfonyl)piperazine hydrochloride
  • Molecular weight

    313.80
  • Molecular formula

    C13H15N3O2S.HCl
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Hagiwara M  et al. Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives. Mol Pharmacol 32:7-12 (1987). Read more (PubMed: 2955213) »
  • Harvath L  et al. Inhibition of human neutrophil chemotaxis by the protein kinase inhibitor, 1-(5-isoquinolinesulfonyl) piperazine. J Immunol 139:3055-61 (1987). Read more (PubMed: 2822802) »

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