Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab188002 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
  • Pathway
    Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.
  • Sequence similarities
    Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
  • Domain
    The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1 acyl sn glycerol 3 phosphate acyltransferase delta antibody
    • 1 acylglycerol 3 phosphate O acyltransferase 4 antibody
    • 1 AGP acyltransferase 4 antibody
    • 1 AGPAT4 antibody
    • 1-acyl-sn-glycerol-3-phosphate acyltransferase delta antibody
    • 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) antibody
    • 1-acylglycerol-3-phosphate O-acyltransferase 4 antibody
    • 1-AGP acyltransferase 4 antibody
    • 1-AGPAT 4 antibody
    • AGPAT4 antibody
    • dJ473J16.2 antibody
    • LPAAT delta antibody
    • LPAAT-delta antibody
    • Lysophosphatidic acid acyltransferase delta antibody
    • Lysophosphatidic acid acyltransferase-delta (LPAAT-delta) antibody
    • PLCD_HUMAN antibody
    • RP3 473J16.2 antibody
    see all

Images

  • Immunohistochemistry of formalin-fixed paraffin embedded human testis tissue labeling 1-AGP acyltransferase 4 with ab188002 at 1/500 dilution

References

This product has been referenced in:
  • Pagliuso A  et al. Golgi membrane fission requires the CtBP1-S/BARS-induced activation of lysophosphatidic acid acyltransferase d. Nat Commun 7:12148 (2016). Read more (PubMed: 27401954) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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