Key features and details
- Potent α-glycosidase inhibitor. Antihyperglycemic agent.
- CAS Number: 19130-96-2
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Streptomyces sp.
Product name1-Deoxynojirimycin, alpha-glycosidase inhibitor
DescriptionPotent α-glycosidase inhibitor. Antihyperglycemic agent.
Biological descriptionPotent α-glycosidase inhibitor (IC50 = 30 nM). Antihyperglycemic agent. Downregulates SGLT1, Na+/K+-ATP and GLUT2 expression. Decreases MCP-1 and TNF-α levels. Shows antidiabetic, antiviral, antiobesity and anti-inflammatory effects in vivo. Orally active.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144834 has not yet been referenced specifically in any publications.