1-Isothiocyanato-8-(methylsulfinyl)-octane, Quinone reductase inducer (ab142900)

Overview

  • Product name

    1-Isothiocyanato-8-(methylsulfinyl)-octane, Quinone reductase inducer
  • Description

    Potent quinone reductase inducer
  • Alternative names

    • 8-methylsulfinyloctyl
  • Biological description

    Potent quinone reductase inducer (IC50 = 0.5 μM). Antioxidant, antimicrobial and anticancer agent. Active in vitro.
  • Purity

    > 98%
  • CAS Number

    75272-81-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-Isothiocyanato-8-methylsulfinyloctane
  • Molecular weight

    233.40
  • Molecular formula

    C10H19NOS2
  • PubChem identifier

    9794659
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CS(=O)CCCCCCCCN=C=S
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Stotz HU  et al. Role of camalexin, indole glucosinolates, and side chain modification of glucosinolate-derived isothiocyanates in defense of Arabidopsis against Sclerotinia sclerotiorum. Plant J 67:81-93 (2011). Read more (PubMed: 21418358) »
  • Rose P  et al. 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis 21:1983-8 (2000). Read more (PubMed: 11062158) »

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