Overview

  • Product name

    1-Naphthohydroxamic acid, HDAC8 inhibitor
  • Description

    Potent, cell-permeable and selective HDAC8 inhibitor
  • Alternative names

    • Compound 2
    • HDAC inhibitor XIX
  • Biological description

    Potent, cell-permeable and selective histone deacetylase inhibitor (HDAC8) inhibitor (IC50 = 14 μM). Anticancer agent. Active in vitro.
  • Purity

    > 99%
  • CAS Number

    6953-61-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Krennhrubec K  et al. Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors. Bioorg Med Chem Lett 17:2874-8 (2007). Read more (PubMed: 17346959) »

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