Recombinant Anti-12 Lipoxygenase/ALOX12 antibody [EPR11380(B)] (ab168384)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR11380(B)] to 12 Lipoxygenase/ALOX12
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-12 Lipoxygenase/ALOX12 antibody [EPR11380(B)]
See all 12 Lipoxygenase/ALOX12 primary antibodies -
Description
Rabbit monoclonal [EPR11380(B)] to 12 Lipoxygenase/ALOX12 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Human
Predicted to work with: Rat -
Immunogen
Synthetic peptide corresponding to Human 12 Lipoxygenase/ALOX12.
Database link: P18054 -
Positive control
- A431, Human spleen and Human fetal liver lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR11380(B) -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab168384 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/5000. Predicted molecular weight: 76 kDa.
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Notes |
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WB
1/1000 - 1/5000. Predicted molecular weight: 76 kDa. |
Target
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Function
Oxygenase and 14,15-leukotriene A4 synthase activity. -
Pathway
Lipid metabolism; leukotriene D4 biosynthesis. -
Sequence similarities
Belongs to the lipoxygenase family.
Contains 1 lipoxygenase domain.
Contains 1 PLAT domain. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 239 Human
- Entrez Gene: 287454 Rat
- Omim: 152391 Human
- SwissProt: P18054 Human
- SwissProt: F1LQ70 Rat
- Unigene: 654431 Human
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Alternative names
- 12 LOX antibody
- 12(S) lipoxygenase antibody
- 12-lipoxygenase antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab168384 has been referenced in 1 publication.
- Yang XH et al. 12-Lipoxygenase promotes epithelial-mesenchymal transition via the Wnt/ß-catenin signaling pathway in gastric cancer cells. Onco Targets Ther 12:5551-5561 (2019). PubMed: 31371993