Product name1,3-Dipropyl-8-p-sulfophenylxanthine, Adenosine receptor antagonist
DescriptionWater soluble adenosine receptor antagonist with slight selectivity for A1 receptors. Ecto-phosphodiesterase inhibitor.
- 4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)benzenesulfonic Acid
Water soluble adenosine receptor antagonist with slight selectivity for A1 receptors. Ecto-phosphodiesterase inhibitor.
Chemical name4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)benzenesulfonic acid
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewDMSO, water (0.43 mg/ml)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Newell EA et al. 2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-a and CXCL10 production from activated primary murine microglia via A2A receptors. Brain Res 1594:27-35 (2015). Read more (PubMed: 25451117) »
- Jackson EK & Gillespie DG Extracellular 2',3'-cAMP-adenosine pathway in proximal tubular, thick ascending limb, and collecting duct epithelial cells. Am J Physiol Renal Physiol 304:F49-55 (2013). Read more (PubMed: 23077101) »
- Jackson EK et al. Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney. Am J Physiol Renal Physiol 303:F1000-5 (2012). Read more (PubMed: 22874760) »
- Jackson EK et al. Extracellular 2,3-cyclic adenosine monophosphate is a potent inhibitor of preglomerular vascular smooth muscle cell and mesangial cell growth [corrected]. Hypertension 56:151-8 (2010). Read more (PubMed: 20516392) »