13(S)-Hydroxyoctadeca-9Z,11E-dienoic acid (13-HODE), Oxidative metabolite of linoleic acid (ab141652)

Overview

  • Product name

    13(S)-Hydroxyoctadeca-9Z,11E-dienoic acid (13-HODE), Oxidative metabolite of linoleic acid
  • Description

    Oxidative metabolite of linoleic acid
  • Biological description

    Oxidative metabolite of linoleic acid generated via 15-lipoxygenase. Mitogenic signalling molecule. PPAR agonist.
  • Purity

    > 99%
  • CAS Number

    29623-28-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (9Z,11E,13S)-13-Hydroxyoctadeca-9,11-dienoic acid
  • Molecular weight

    296.50
  • Molecular formula

    C18H32O3
  • PubChem identifier

    6443013
  • Storage instructions

    Store at -20°C (desiccating conditions).
  • Solubility overview

    Supplied in ethanol (50 µg/ml)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCC(C=CC=CCCCCCCCC(=O)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Dauchy RT  et al. A new apparatus and surgical technique for the dual perfusion of human tumor xenografts in situ in nude rats. Comp Med 62:99-108 (2012). Read more (PubMed: 22546915) »
  • Hill SM  et al. Melatonin and associated signaling pathways that control normal breast epithelium and breast cancer. J Mammary Gland Biol Neoplasia 16:235-45 (2011). Read more (PubMed: 21773809) »
  • Kämmerer I  et al. 13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages. Lipids Health Dis 10:222 (2011). Read more (PubMed: 22129452) »

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