14,15-Leukotriene A4 methyl ester, Inhibitor of Leukotriene A4 hydrolase (ab141696)

Overview

  • Product name

    14,15-Leukotriene A4 methyl ester, Inhibitor of Leukotriene A4 hydrolase
  • Description

    Inhibitor of Leukotriene A4 hydrolase
  • Biological description

    Inhibitor of Leukotriene A4 hydrolase
  • Purity

    > 99%
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Methyl 4-[(2S,3S)-3-[(1E,3E,5Z,8Z)-tetradeca-1,3,5,8-tetraenyl]oxiran-2-yl]butanoate
  • Molecular weight

    332.50
  • Molecular formula

    C21H32O3
  • PubChem identifier

    6478221
  • Storage instructions

    Store at -80°C.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCC[C@@H]1O[C@H]1/C=C/C=C/C=C\C/C=C\CCCC(=O)OC
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Söderström M  et al. On the nature of leukotriene C4 synthase in human platelets. Arch Biochem Biophys 294:70-4 (1992). Read more (PubMed: 1312812) »
  • Ohishi N  et al. Leukotriene A4 hydrolase in the human lung. Inactivation of the enzyme with leukotriene A4 isomers. J Biol Chem 262:10200-5 (1987). Read more (PubMed: 3038871) »
  • Bryant RW  et al. Leukotriene formation by a purified reticulocyte lipoxygenase enzyme. Conversion of arachidonic acid and 15-hydroperoxyeicosatetraenoic acid to 14, 15-leukotriene A4. J Biol Chem 260:3548-55 (1985). Read more (PubMed: 2982864) »

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