15-Acetyl-deoxynivalenol (15-ADON), Type B trichothecene mycotoxin (ab143561)

Overview

  • Product name

    15-Acetyl-deoxynivalenol (15-ADON), Type B trichothecene mycotoxin
  • Description

    Type B trichothecene mycotoxin
  • Biological description

    Type B trichothecene mycotoxin. Deoxynivalenol (ab143487) and 3-Acetyldeoxynivalenol (ab143561) analog. Protein synthesis inhibitor. Binds to rRNA. Induces TNF-α, IL-1β, IL-6, CXCL-2, CCL-2 and CCL-7 mRNA expression. Shows emetic effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    88337-96-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Wu W  et al. Effects of oral exposure to naturally-occurring and synthetic deoxynivalenol congeners on proinflammatory cytokine and chemokine mRNA expression in the mouse. Toxicol Appl Pharmacol : (2014). Read more (PubMed: 24793808) »
  • Wu W  et al. Comparison of emetic potencies of the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol. Toxicol Sci 131:279-91 (2013). Read more (PubMed: 22997060) »
  • Mirocha CJ  et al. Variation in Deoxynivalenol, 15-Acetyldeoxynivalenol, 3-Acetyldeoxynivalenol, and Zearalenone Production by Fusarium graminearum Isolates. Appl Environ Microbiol 55:1315-6 (1989). Read more (PubMed: 16347922) »

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